Lewis Stevens (Dougray Scott) is an overworked doctor and devoted single dad heading home with his young son on the last train from London. When he strikes up a relationship with a beautiful and flirtatious stranger, Lewis believes life is finally looking up. But events then take a dark turn when Lewis discovers the guard has mysteriously vanished and the brakes have been sabotaged. Unknown to the handful of remaining passengers, a vengeful sociopath has taken control of the train and is hell bent on crashing it, taking his passengers with him to the grave. As the speeding locomotive ploughs through stations and level crossings, the body count rises and panic turns to terror. Lewis realises that the police are powerless to stop the diesel-powered 'slammer' train, and the desperate passengers must find their own way out of this nightmare. Lewis takes the lead in a series of increasingly perilous missions to stop the train before the driver can realise his dark plan….
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