Three cynical best friends since high school, Regan, Gena and Katie, are outraged to learn their chubby but sweet friend Becky is going to be the first of the gang to get married. Gena and Katie are still single, Regan has been pressuring her boyfriend of four years, Frank, to propose. When Becky asks neurotic Regan to help plan the wedding and be the Maid of honour, she is furious. Six months later, the day before the wedding, resentfull Regan is bossing around staff and guests, while Katie and Gena are ready to party. Everything starts going wrong. While they try to drown their sorrows at the bar, they run into Gena’s high school sweetheart Clyde. They still have feelings for each other. Then, during rehearsal dinner, things start going awry when Gena drunkenly gives a toast mentioning Becky’s high school bulimia. When Katie forgets to cancel a stripper she hired for the bachelorette party, the bride ends up furious and tells the 3 friends not to come to the wedding ceremony unless they are sober and behave like adults. Nevertheless, the girls decide to make the most of the night and they get on a wild ride down the road to this matrimony.
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