World weary, Dublin stand up comedienne, Kate McLoughlin is at breaking point. Her will to live is waning. When her morbid prayers are answered in the form of a cancer diagnosis, little does she know that getting out of this life is going to prove a lot more difficult that she thinks. To placate her family, she begrudgingly agrees to undergo chemotherapy. Armed with staggering levels of cynicism and a plethora of blackly comic jokes, her exit strategies are constantly upended when she encounters four powerful women whose unsolicited friendships challenge her, soften her and ultimately blow open her shut down heart.